Endocrine Abstracts

Objective: The presence of APA has been reported in patients with autoimmune polyendocrinopathies, but their prevalence in type 1 diabetes mellitus (T1D) is still unknown. The aim of this study was to assess APA prevalence in T1D patients as compared to patients with type 2 diabetes mellitus (T2D) and healthy subjects.Research design and methods: The presence of APA was assessed by indirect immunofluorescence (IF) technique, with bovine adrenal gland and...

Introduction: Both GH and IGF1 have important effects on the heart mass and contractility and deficiency of either hormone is associated with increased cardiovascular morbidity and mortality. GH/IGF1 axis abnormalities (mostly primary or secondary IGF1-D) are frequent in adult patients with β-thalassemia major (β-Thal). IGF1-D could therefore contribute with iron overload to the heart’s damage of β-Thal patients, but this question has been little investigat...